Proximity to traffic linked to increased dementia risk and brain structural changes

18/11/2023

$Population attributable fraction of all-cause dementia incidence of residential proximity and traffic-related air pollution exposures. We defined residential proximity (≤1,000 m) and nitrogen oxide pollution (≥44.0 μg/m3) based on sample distribution, and nitrogen dioxide pollution (≥20.0 μg/m3), PM10 pollution (≥15.0 μg/m3), and PM2.5 pollution (≥10.0 μg/m3) based on interim targets established by WHO air quality guidelines. Fitted Cox regression models with age as the time scale were used to estimate the attributable fraction for each exposure, further controlling for sex, ethnic background, education, current smoking, alcohol intake, physical activity, obesity, depressed mood, hypertension, diabetes, stroke, and coronary heart disease. Dots represent point estimates, while lines and shadows represent fitted smooth splines. Credit: Health Data Science (2023). DOI: 10.34133/hds.0091$
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