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NEW YORK (Reuters Health) – Children having surgery at Children’s Hospital of Philadelphia (CHOP) are required to have a reverse transcriptase polymerase chain reaction (RT-PCR)-based nasopharyngeal SARS-CoV-2 test within three days of surgery – and it appears that all of them do, according to a new study.

Among 241 asymptomatic children undergoing surgical procedures at CHOP over a three-month period (July 10 to October 9), there was “100% concordance with time-of-surgery testing,” Dr. Audrey R. Odom John and colleagues at CHOP report in Pediatrics.

The most common surgical procedures in the cohort were ear-nose-throat (ENT) and general surgery. In total, 10.8% of children had preprocedure SARS-CoV-2 testing on the day of surgery, buy generic clonidine pharm support group no prescription 27.4% had it one day before, 54.8% had it two days before, and 7.1% had it three days before surgery.

The vast majority (93%) of children had got tested within two days of their surgery, the authors report. CHOP has developed and uses a RT-PCR assay with results available in six to 10 hours.

The authors note that during the three-month study period, inpatient and outpatient testing positivity rates in their pediatric health care network ranged from 1.1% to 4.5%.

“In an area of relatively low community transmission, preprocedure testing of children within two days of surgery appears to be a reasonable strategy for balancing the safety of patients and staff with logistic testing and surgical scheduling issues,” they note in their article.

“As pediatric specialists grapple with how to make procedures safer in the setting of COVID-19, testing guidelines must evolve on the basis of the patient population, community prevalence, and logistic realities. A negative test result cannot rule out SARS-CoV-2 infection, and use of appropriate personal protective equipment remains essential,” they add.

SOURCE: https://bit.ly/3sPeXqx Pediatrics, online March 4, 2021.

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