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The risk for migraine is increased in lightly pigmented adults, according to a study published online May 10 in Brain Sciences.

Magdalena Kobus, from the University of Lodz in Poland, and colleagues examined the potential association between skin pigmentation and migraine in 148 adults (33 men, 115 women) with migraine and 107 controls (43 men, 64 women). Parameters of skin pigmentation were measured.

The researchers observed an increased risk for migraine in lightly pigmented adults. The risk for migraine was increased more than threefold for individuals with a low melanin index (odds ratios, 3.53 and 3.73 in women and men, pharmacy technician pay rates respectively). Fair phenotype, resulting from lightly pigmented skin, was associated with the prevalence of migraine.

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