Colonoscopy and a healthy lifestyle: the risk of colon cancer lower
Colorectal cancer is one of the most common cancers in Germany. To protect yourself, you should take after a certain age, regular preventive health check-UPS. Also very important to a healthy lifestyle with a balanced diet and adequate exercise, but it is.
Although there are still many types of cancer, the trigger is not known, but in the meantime, we know of many factors that can cause different cancers – but not necessarily must. To protect yourself from cancer, you should minimize these risk factors. Experts now have proof that every person can reduce their individual risk of colorectal cancer.
Many factors affect the risk of cancer
Such as the German cancer research center (DKFZ) in a recent communication, writes a lot of factors, the risk of colon cancer. This includes, especially, the personal life style, apart from the genetic risk.
Researchers at the DKFZ have now compared for the first time, all known risk factors to calculate the risk of colon cancer in absolute Numbers.
It was clear that every person can lower their individual risk by a healthy lifestyle – no matter what genetic risk he brings. And the colonoscopy is the most effective tool to reduce the individual risk to develop colorectal cancer, drastically.
All the risk factors analyze
Colorectal cancer is currently in Germany for men the third most common, and for females the second most common cancer. Risk factors there are many.
In addition to genetic factors – tiny variations in the genome (SNPs, single nucleotide polymorphisms) that increase the risk or mitigate the can – plays, in particular, the life-style a vital role.
Risk factors include Smoking, Obesity, poor diet and lack of exercise.
In contrast, screening colonoscopy, the precursors of colorectal cancer detect is. The Removal of these precursors is able to reduce the risk of colon cancer is crucial.
“The individual risk factors are already well studied – however, they have been considered so far in the rule, separately,” according to Michael Hoffmeister of the German cancer research center (DKFZ).
“The aim of our study was to analyze all the risk factors together, to work out how the individual colorectal cancer risk differ according to the genetic risk and lifestyle, and what is the role of colonoscopy plays.”
Absolute colorectal cancer risk calculated
The DKFZ researchers to Hoffmeister analyzed the data of more than 4,200 people with colorectal cancer and more than 3,300 control subjects and calculated the absolute risk, after the age of 50. Developing a birthday within the next 30 years to cancer.
“The Absolute risks are convey in the communication, for example between doctor and Patient, is usually easier to as relative risks,” explains Hoffmeister is the way to go.
The experts classified the Participants on the basis of genetic risk and lifestyle factors in each of the three groups with high, medium or low risk and considered if ever a colonoscopy was performed.
Individual risk-reducing regardless of the genetic Background
“The most important result of our study was that even reduced in people with increased genetic risk, the risk of developing a disease, actually cancer of the colon, by colonoscopy and a healthy life-style drastically,” explains Prudence Carr, the first author of the study.
The estimates showed that men with a medium genetic risk of, an average life style, who had not perceived a colonoscopy, a 30-year-risk for colorectal cancer from 7.4 per cent.
In other words: Of a hundred men with this risk profile will develop seven to eight within the next 30 years to cancer. In men with a similar genetic Background who lived but healthier, and a colonoscopy had perceived was the risk of only 1.9 percent.
“The special feature of our study is that we were able to demonstrate and illustrate: Regardless of the genetic Background someone was born, you can be individual colorectal cancer risk significantly reduced,” says Hoffmeister.
The results of the study were published in the journal “Gastroenterology”. (ad)